Agent 47 has a new, high-profile contract. On February 25, 2026, IO Interactive and IGN debuted the official briefing trailer for the “Patient Zero Requiem” Elusive Target mission in Hitman: World of Assassination. This special event features the digital likeness of blockbuster actress Milla Jovovich as the target, Lilith Devereux [00:55]. Available to play for free from February 25 to March 24, 2026, this mission brings a cinematic level of intrigue to the stealth action franchise [01:00].
The mission takes place at the opulent estate of Gregory Carlyle, where Devereux is attending a fundraiser for the Ether Corporation [00:11]. As the prospective new CEO, her rapid rise within Ether following the convenient deaths of her predecessors has raised suspicions both within the company and among the Carlyle family [00:19, 00:38]. Agent 47 is tasked with navigating the security-heavy event, identifying the target, and eliminating her without being detected. With the “Patient Zero” moniker hinting at a deeper, more dangerous plot, players must use all their skills to complete the contract and unravel the mystery surrounding Devereux’s rise to power.
🌟 Section 1: What is the video about?
The briefing trailer provides essential mission details and a cinematic look at the target. Key highlights include:
The Target: Lilith Devereux (played by Milla Jovovich), the ambitious new CEO candidate for Ether Corporation [00:06, 00:55].
The Location: A high-stakes fundraiser at the Carlyle estate, a location known for its complex layout and tight security [00:11].
The Context: Devereux's “meteoric rise” follows the suspicious deaths of former Ether executives, including Nellas Duval, Silvio Caruso, and Francesca De Santis [00:22].
The Conflict: A rival faction within the Carlyle family has hired the ICA to eliminate Devereux, fearing she is a threat to their power [00:38].
The Warning: Diana Burnwood warns 47 that this may be “more than just a family feud,” urging caution as he approaches the mission [00:46].
Limited-Time Event: The trailer confirms the mission is available for a one-month window starting February 25, 2026 [01:00].
🎯 Section 2: Main Message or Purpose
The primary objective of this video is to brief and excite players about the new “Patient Zero Requiem” Elusive Target mission. It aims to provide value by offering a cinematic preview of the target, the setting, and the overarching plot, while encouraging players to jump into the game during the limited-time event. The inclusion of Milla Jovovich as a celebrity target adds a unique and high-profile dimension to the Hitman experience.
📊 Section 3: Key Video Data
🎁 Section 4: Reasons to Watch
Celebrity Target: See Milla Jovovich’s transformation into the calculating and dangerous Lilith Devereux [00:06, 00:55].
Mission Strategy: Get a first look at the Carlyle estate during the fundraiser and start planning your approach [00:11, 00:50].
Lore Deep-Dive: Learn about the corporate intrigue and suspicious deaths that paved the way for Devereux's rise at Ether [00:22].
Cinematic Briefing: Enjoy the high-quality storytelling and voice acting that are hallmarks of the Hitman franchise [00:01].
Time-Sensitive Info: Ensure you have all the dates and details needed to take on this limited-time contract [01:00].
🔑 Suggested Keywords
Hitman World of Assassination Patient Zero Requiem
Milla Jovovich Hitman Elusive Target Trailer
Lilith Devereux Mission Briefing
Hitman 3 Carlyle Estate Fundraiser Event
Free Hitman Elusive Target Missions 2026
✨ Conclusion
The “Patient Zero Requiem” Elusive Target mission is a thrilling addition to the Hitman: World of Assassination legacy, blending real-world star power with high-stakes stealth gameplay. With Lilith Devereux in your sights, the world is waiting to see if Agent 47 can once again complete the impossible.