If you don't know how to get life runes in Path of Exile Settlers of Kalguur here is a guide that will help you.
Stuck upgrading your Runesmith? You probably need Life Runes. Not particularly rare, but it's hard to get if you spent most of the campaign leveling Kingsmarch. This will guide you to farm Life Runes needed for your Runesmith on Path of Exile 3.25 Settlers of Kalguur league.
How to Get Life Runes in Path of Exile Settlers of Kalguur
Life Runes are of mid-tier rune rarity, less elusive than either time or power runes, but more elusive than Sun or bound runes. Though there are some ways to gain runes, the most reliable source is through the shipping mechanic in Kingsmarch.
Certain ports, identified with a silver or runic flag in the image, give runes as an extra reward for trades when rewards are received. Although one cannot exactly target Life Runes, shipping routes can be optimized to increase one's chances of getting them.
In particular, the efficiency of the Riben Fell port comes at about 30 minutes. Be it Wheat or Verisium Ore, ship whatever resource, and get runes as long as you trade with Riben Fell or any other flagged port.
Ultimately, this goes down to time and chance. Other rune-yielding ports require increased shipping rank, whereas right from the start when you unlock shipping in Kingsmarch, Riben Fell is one of the more consistent starting points for your rune farming journey.
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